WHAT IS ESKETAMINE?

  • Prescription nasal spray for treatment-resistant depression (TRD): This means it’s used when traditional medications haven’t worked well enough.
  • Works differently than other antidepressants: It targets a different pathway in the brain called the glutamate system.
  • Used with other treatments, like therapy: It’s most effective when combined with other approaches.
  • May offer faster relief: Some people feel better within hours of the first dose.

WHAT TO EXPECT?

How will I take ESKETAMINE?

You will take ESKETAMINE nasal spray yourself, under the supervision of a healthcare provider in a healthcare setting. Your healthcare provider will show you how to use the ESKETAMINE nasal spray device. Your healthcare provider will tell you how much ESKETAMINE you will take and when you will take it. Follow your ESKETAMINE treatment schedule exactly as your healthcare provider tells you to. During and after each use of the ESKETAMINE nasal spray device, you will be checked by a healthcare provider who will decide when you are ready to leave the healthcare setting. You will need to plan for a caregiver or family member to drive you home after taking ESKETAMINE. If you miss an ESKETAMINE treatment, your healthcare provider may change your dose and treatment schedule. Some people taking ESKETAMINE get nausea and vomiting. You should not eat for at least 2 hours before taking ESKETAMINE and not drink liquids at least 30 minutes before taking ESKETAMINE. If you take a nasal corticosteroid or nasal decongestant medicine take these medicines at least 1 hour before taking ESKETAMINE.

What should I avoid while taking ESKETAMINE?

Do not drive, operate machinery, or do anything where you need to be completely alert after taking ESKETAMINE. Do not take part in these activities until the next day following a restful sleep. See “What is the most important information I should know about ESKETAMINE?”

The most common side effects of ESKETAMINE when used along with an antidepressant taken by mouth include:

feeling disconnected from yourself, your thoughts, feelings and things around you

dizziness, nausea, feeling sleepy, spinning sensation, decreased feeling of sensitivity (numbness), feeling anxious, lack of energy, increased blood pressure, vomiting, feeling drunk, feeling very happy or excited

If these common side effects occur, they usually happen right after taking ESKETAMINE and go away the same day. These are not all the possible side effects of ESKETAMINE.

What are the possible side effects of ESKETAMINE?

Increased blood pressure. ESKETAMINE can cause a temporary increase in your blood pressure that may last for about 4 hours after taking a dose. Your healthcare provider will check your blood pressure before taking ESKETAMINE and for at least 2 hours after you take ESKETAMINE. Tell your healthcare provider right away if you get chest pain, shortness of breath, sudden severe headache, change in vision, or seizures after taking ESKETAMINE.
Problems with thinking clearly. Tell your healthcare provider if you have problems thinking or remembering.
Bladder problems. Tell your healthcare provider if you develop trouble urinating, such as a frequent or urgent need to urinate, pain when urinating, or urinating frequently at night.

COST & COVERAGE?

Esketamine treatments have been covered by most insurance companies. Please contact us for further information and to schedule an initial evaluation.